Imagine sitting across from your doctor in his office…

He’s trying to talk you into a new treatment.

It’s irreversible.

It may not extend your life by a single day.

And nobody knows if it’s safe long-term.

Who on Earth would EVER agree to that?

Well, prepare yourself, friend… because you might be in your doctor’s office, having this exact conversation, sooner than you think.

There’s a new cholesterol treatment wending its way through clinical trials right now.

Cholesterol-obsessed mainstream doctors are already raving about it… and are desperate to see it approved.

But I think it’s absolutely terrifying… and I’ll show you exactly why.

First off, mainstream medicine’s fixation with cholesterol has been wrong at every turn.

I don’t know how they have any credibility left.

When statins first hit the market, we were told that lowering cholesterol would send heart attacks and strokes plummeting like a stone.

Dead wrong.

For people without heart disease, you have to give 104 patients statins for five years to stop a single heart attack.

Even for people WITH heart disease, you have to treat 39.

Let’s be clear – these are WORSE ODDS than you’d get at a roulette table in Vegas.

If lowering cholesterol meaningfully prevented heart attacks and strokes, the numbers on statins would be a heck of a lot better than they are.

But where statins excel is at causing side effects. They’ve left countless people with crippling muscle pain… and have been linked to everything from liver damage to diabetes.

You’d think the last thing on Earth anyone would want is an even MORE aggressive cholesterol treatment.

But that may be exactly what’s coming our way…

CRISPR gene-editing technology is now going through clinical trials, with the Phase 1 trial complete.

This is an IV treatment that disables a gene in your liver that produces proteins that can raise LDL cholesterol and triglycerides.

Sure enough, it lowered these numbers by as much as half, and mainstream doctors and researchers started raving about it.

One doctor even wondered whether the landscape for cholesterol management could be “on the verge of a profound shift.”

Yeah, let’s hope not.

This isn’t like popping a pill you can stop at any time.

With the CRISPR technology, you’re allowing changes to the genes within your body. And if dangerous side effects emerge – as they did with previous cholesterol treatments – there may be no way to completely reverse it.

That should scare the pants off of anyone.

Nobody knows if this stuff is safe long-term… it may be irreversible… and they already seem to be taking a page from the statins playbook.

In the early clinical trials on statins, researchers used cholesterol lowering as a proxy for reducing heart attacks, strokes, and deaths – without measuring whether those benefits actually occurred.

It wasn’t until Big Pharma sold BILLIONS in statins that we learned they don’t meaningfully prevent anything.

I can see the same thing happening here. Doctors are already raving about this technology without knowing if it’s safe or can save a single life.

Not me…

Cholesterol is essential to our bodies and health – every cell membrane in your body is made from it.

And we need to stop this obsession with vilifying cholesterol and lowering it at any cost.

That has already gotten us into plenty of trouble. And I think there’s more trouble ahead.

In Your Corner,

Dr. Allan Spreen

In Case You Missed It

Sources:

  • Laffin, L. J., Nicholls, S. J., Scott, R. S., Clifton, P. M., Baker, J., Sarraju, A., Singh, S., Wang, Q., Wolski, K., Xu, H., Nielsen, J., Patel, N., & Duran, J. M. (2025). Phase 1 trial of CRISPR‑Cas9 gene editing targeting ANGPTL3. New England Journal of Medicine, 393(21), 2119–2130. https://doi.org/10.1056/NEJMoa2511778
  • Newman, D. (2015, January 10). Statins for heart disease prevention (without prior heart disease). theNNT. https://thennt.com/nnt/statins-for-heart-disease-prevention-without-prior-heart-disease-2/
  • Newman, D. (2013, November 2). Statins for heart disease prevention (with known heart disease). theNNT. https://thennt.com/nnt/statins-for-heart-disease-prevention-with-known-heart-disease/
  • Medscape. (2026, February 13). The promise of one and done CRISPR‑based lipid lowering. Medscape. https://www.medscape.com/viewarticle/promise-one-and-done-crispr-based-lipid-lowering-2026a100041q


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Allan Spreen, M.D.
Dr. Allan Spreen, Chief Medical Advisor

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