Could NIGHTMARES Signal a Serious Autoimmune Disease?
Dear Reader,
We all have the occasional bad dream…
But what if your nightmares were actually trying to tell you something about your health?
A groundbreaking new study suggests that increasingly vivid and disturbing nightmares could be an early warning sign of lupus and other autoimmune diseases.
And the implications are shocking…
The study, published in eClinicalMedicine, focused on systemic lupus erythematosus (SLE), a complex autoimmune disease that can affect multiple organ systems, including the brain and nervous system (known as neuropsychiatric SLE or NPSLE).
Researchers surveyed 676 lupus patients and found that a staggering 61% of those who experienced hallucinations reported having increasingly disturbed dreams before the onset of the hallucinations. This connection was less pronounced in other systemic autoimmune rheumatic diseases (SARDs) at 34%, suggesting that nightmares might be a more specific warning sign for lupus.
But what’s the connection between nightmares and autoimmune diseases?
The answer may lie in the complex interplay between the immune system and the brain. Autoimmune diseases occur when the body’s immune system mistakenly attacks healthy cells and tissues, leading to inflammation and damage in various organs, including the brain.
The study’s authors hypothesize that the increase in nightmares may be a result of early, subtle changes in the brain caused by the autoimmune process.
The types of nightmares reported by lupus patients in the study were often disturbing and intense, with some describing dreams of being crushed, trapped, or attacked, while others reported violent or frightening scenarios involving themselves or their loved ones.
And it gets even more bizarre…
Researchers also introduced the concept of “daymares” to describe vivid, dream-like experiences that occur during waking hours. Many patients had a “lightbulb” moment when this term was used, recognizing that they had experienced similar phenomena but had not previously identified them as hallucinations.
While nightmares alone may not be enough to diagnose an autoimmune disease, they could serve as an important early warning sign, prompting patients and their healthcare providers to be more vigilant for other symptoms of a flare-up.
So, if you’ve been experiencing increasingly vivid and disturbing nightmares, don’t brush them off as just bad dreams. Talk to your doctor about your concerns and be on the lookout for other signs of autoimmune disease activity, such as changes in mood, cognitive function, or sensory perception.
By paying attention to your dreams and working with your healthcare team, you may be able to detect and manage autoimmune disease flares earlier, potentially preventing more serious complications down the line.
To sweet dreams and better health,
Rachel Mace
Managing Editorial Director, e-Alert
with contributions from the research team
P.S. Odd “root” reigns in autoimmune disease?
Sources:
Amin, Z., & Knight, E., et.al. (2024) Disrupted dreaming sleep and ‘daymares’ as early warning signs for autoimmune disease. eClinicalMedicine.


