“Internal Joint Switch” Slashes Pain 40% (Here’s How to Activate It)
If arthritis has been controlling your life for years…
If you’re tired of fingers locking up… wincing when you get up from a chair… or feeling like your knees are full of gravel… you’ve probably wished your arthritis had an “off” switch.
Just a simple switch you could flip to turn down those constant aches and pains…
Well, breakthrough science has finally found it… and research is proving that activating this “joint switch” could hold the key to slashing your arthritis pain levels by 40%.
So how do you do it?
All it takes is a simple, all-natural compound… one that we’ve been telling HSI readers about for years.
We’ve always known that rheumatoid arthritis is caused by your immune system attacking your joints.
But here’s the truth that’s been hiding in plain sight all along – and that far too many doctors ignore.
The same thing can happen with regular osteoarthritis – your immune system can target your joints and speed up the destruction of cartilage.
You see, as cartilage breaks down, it can trigger your immune system to create inflammation and even deploy T-cells, which can further damage your joints.
And once that attack begins? It doesn’t matter how many pills you take or how many injections you endure—you can’t rebuild something your immune system is actively tearing apart.
That’s where the real breakthrough comes in.
It’s called undenatured type II collagen peptide—UC-II— and it’s a special compound that comes from chicken cartilage.
If you’re an HSI member, you may already be taking UC-II – we started telling our members about it years ago.
But this latest science required an update – because it looks like UC-II can “retrain” your immune system to STOP attacking your joints.
Basically, as you take UC-II, your body develops an “oral tolerance” to the collagen. Then, it’s like UC-II flips an “Internal Joint Switch” that turns down your immune system’s attacks on your joints.
And that results in REAL pain relief you can feel…
In one randomized human trial on knee osteoarthritis, UC-II slashed pain levels by an impressive 40% and produced a 33% improvement in WOMAC scores (a standard, combined measure of knee pain and mobility).
And when researchers compared UC-II to glucosamine and chondroitin, two of the top joint supplements around, UC-II delivered far better results — with major improvements in pain, stiffness, and daily function.
And what about rheumatoid arthritis – the type of arthritis we most commonly associate with an immune system attack? Well, UC-II improved swollen and tender joints by up to 30% — as much as 10 TIMES better than placebo.
UC-II isn’t trying to patch up cartilage. It’s doing something far more fundamental: It’s telling your immune system to stop attacking it.
Once that internal sabotage ends, inflammation cools, pain begins to settle, and mobility finally has room to return.
If you want to try it, look for UC-II or undenatured type II collagen on the label. The clinically tested dose is just 40 mg once daily.
To steadier steps and calmer joints,
Rachel Mace
Managing Editorial Director, e-Alert
with contributions from the research team
Sources:
- Crowley, D. C., Lau, F. C., Sharma, P., Evans, M., Guthrie, N., Bagchi, M., & Bagchi, D. (2009). Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee: A clinical trial. International Journal of Medical Sciences, 6(6), 312–321. https://www.medsci.org/v06p0312.htm
- Lugo, J. P., Saiyed, Z. M., & Lane, N. E. (2016). Efficacy and tolerability of an undenatured type II collagen supplement in modulating knee osteoarthritis symptoms: A multicenter randomized, double-blind, placebo-controlled study. Nutrition Journal, 15, 14. https://pubmed.ncbi.nlm.nih.gov/26822714/
- Kumar, P., Simental-Mendía, M., Peña-Martínez, V. M., Vilchez-Cavazos, F., & others. (2023). Efficacy of undenatured collagen in knee osteoarthritis: Review of the literature with limited meta-analysis. American Journal of Translational Research, 15(9), 5124–5135. https://pubmed.ncbi.nlm.nih.gov/37854210/
- Trentham, D. E., Dynesius-Trentham, R. A., Orav, E. J., Combitchi, D., Lorenzo, C., Sewell, K. L., Hafler, D. A., & Weiner, H. L. (1993). Effects of oral administration of type II collagen on rheumatoid arthritis. Science, 261(5129), 1727–1730. https://pubmed.ncbi.nlm.nih.gov/8378772/
- Barnett, M. L., Kremer, J. M., St Clair, E. W., Clegg, D. O., Furst, D., Weisman, M., Fletcher, M. J., Chasan-Taber, S., Finger, E., Morales, A., Le, C. H., & Trentham, D. E. (1998). Treatment of rheumatoid arthritis with oral type II collagen: Results of a multicenter, double-blind, placebo-controlled trial. Arthritis & Rheumatism, 41(2), 290–297. https://pubmed.ncbi.nlm.nih.gov/9485087/
- Lugo, J. P., Saiyed, Z. M., Lau, F. C., Molina, J. P. L., Pakdaman, M. N., Shamie, A. N., & Udani, J. K. (2013). Undenatured type II collagen (UC-II®) for joint support: A randomized, double-blind, placebo-controlled study in healthy volunteers. Journal of the International Society of Sports Nutrition, 10, 48. https://pubmed.ncbi.nlm.nih.gov/24153020/


